Article
Long-term Noninvasive Ventilation in Obesity Hypoventilation Syndrome Without Severe OSA: The Pickwick Randomized Controlled Trial.
Chest - 1 Sept 2020
Masa Juan F, Benítez Iván, Sánchez-Quiroga Maria Á, Gomez de Terreros Francisco J, Corral Jaime, Romero Auxiliadora, Caballero-Eraso Candela, Alonso-Álvarez Maria L, Ordax-Carbajo Estrella, Gomez-Garcia Teresa, González Mónica, López-Martín Soledad, Marin José M, Martí Sergi, Díaz-Cambriles Trinidad, Chiner Eusebi, Egea Carlos, Barca Javier, Vázquez-Polo Francisco J, Negrín Miguel A, Martel-Escobar María, Barbé Ferrán, Mokhlesi Babak
Abstract excerpt
BACKGROUND: Noninvasive ventilation (NIV) is an effective form of treatment in obesity hypoventilation syndrome (OHS) with severe OSA. However, there is paucity of evidence in patients with OHS without severe OSA phenotype. RESEARCH QUESTION: Is NIV effective in OHS without severe OSA phenotype? STUDY DESIGN AND METHODS: In this multicenter, open-label parallel group clinical trial performed at 16 sites in Spain,...
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