Article
"Frozen evolution" of an RNA virus suggests accidental release as a potential cause of arbovirus re-emergence.
PLoS biology - 1 Apr 2020
Pascall David J, Nomikou Kyriaki, Bréard Emmanuel, Zientara Stephan, Filipe Ana da Silva, Hoffmann Bernd, Jacquot Maude, Singer Joshua B, De Clercq Kris, Bøtner Anette, Sailleau Corinne, Viarouge Cyril, Batten Carrie, Puggioni Giantonella, Ligios Ciriaco, Savini Giovanni, van Rijn Piet A, Mertens Peter P C, Biek Roman, Palmarini Massimo
Abstract excerpt
The mechanisms underlying virus emergence are rarely well understood, making the appearance of outbreaks largely unpredictable. Bluetongue virus serotype 8 (BTV-8), an arthropod-borne virus of ruminants, emerged in livestock in northern Europe in 2006, spreading to most European countries by 2009 and causing losses of billions of euros. Although the outbreak was successfully controlled through vaccination by...
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