Article
Clinical importance of extended second field high-resolution HLA genotyping for kidney transplantation.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons - 1 Dec 2020
Senev Aleksandar, Emonds Marie-Paule, Van Sandt Vicky, Lerut Evelyne, Coemans Maarten, Sprangers Ben, Kuypers Dirk, Naesens Maarten
Abstract excerpt
The need for extended second field high-resolution (2F-HR) HLA genotyping in kidney transplantation is debated. In a cohort of 1000 kidney transplants, we evaluated the impact of different HLA genotyping levels on the assignment of donor-specific anti-HLA antibodies (DSA) and investigated whether inference of 2F-HR genotypes from low-resolution (LR) genotypes could be used to correctly assign DSA. Based on LR...
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