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Article

Large-scale second-hit AIP deletion causing a pediatric growth hormone-secreting pituitary adenoma: Case report and review of literature.

Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia - 1 Aug 2020

Gummadavelli Abhijeet, Dinauer Catherine, McGuone Declan, Vining Eugenia M, Erson-Omay E Zeynep, Omay Sacit Bulent

Abstract excerpt

Gigantism (early-onset acromegaly) is a rare pediatric disorder caused by a growth hormone (GH)-secreting pituitary adenoma. Approximately 50% patients of gigantism have a germline mutation, most commonly an inactivating mutation in the aryl-hydrocarbon interacting receptor protein (AIP) gene on chromosome 11q13.2. We present an 11-year-old male patient with a GH-secreting pituitary macroadenoma who presented...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32336638
DOI: 10.1016/j.jocn.2020.04.103

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