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Cell free DNA from respiratory pathogens is detectable in the blood plasma of Cystic Fibrosis patients

23 Apr 2020

Abstract excerpt

Abstract Diagnostically informative microbial cell-free DNA (cfDNA) can be detected from blood plasma during fulminant infections such as sepsis. However, the potential for DNA from airway pathogens to enter the circulation of cystic fibrosis (CF) patients during chronic infective states has not yet been evaluated. We assessed whether patient blood contained measurable quantities of cfDNA from CF respiratory...

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PMID: 32327704
DOI: 10.1038/s41598-020-63970-0

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