Article
Anaplastic Lymphoma Kinase Mutation-Positive Non-Small Cell Lung Cancer.
Thoracic surgery clinics - 1 May 2020
Serritella Anthony V, Bestvina Christine M
Abstract excerpt
The treatment of patients with advanced non-small cell lung cancer with anaplastic lymphoma kinase chromosomal rearrangements has been revolutionized by the development of tyrosine kinase inhibitors (TKIs). Excellent progress has been made over the past decade, with 4 TKIs now approved in the front-line setting. Alectinib is the preferred first-line option based on its efficacy and side-effect profile. The...
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