Article
Therapeutic Potential of Dental Pulp Stem Cells and Leukocyte- and Platelet-Rich Fibrin for Osteoarthritis.
Cells - 15 Apr 2020
Lo Monaco Melissa, Gervois Pascal, Beaumont Joel, Clegg Peter, Bronckaers Annelies, Vandeweerd Jean-Michel, Lambrichts Ivo
Abstract excerpt
Osteoarthritis (OA) is a degenerative and inflammatory joint disorder with cartilage loss. Dental pulp stem cells (DPSCs) can undergo chondrogenic differentiation and secrete growth factors associated with tissue repair and immunomodulation. Leukocyte- and platelet-rich fibrin (L-PRF) emerges in regenerative medicine because of its growth factor content and fibrin matrix. This study evaluates the therapeutic...
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