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Article

Mutations in the tail domain of MYH3 contributes to atrial septal defect.

PloS one - 1 Jan 2020

Maran Sathiya, Ee Robson, Faten Siti Aisyah, Sy Bing Choi, Khaw Kooi Yeong, Erin Lim Swee-Hua, Lai Kok-Song, Wan Ibrahim Wan Pauzi, Mohd Zain Mohd Rizal, Chan Kok Gan, Gan Siew Hua, Tan Huay Lin

Abstract excerpt

Atrial septal defect (ASD) is one of the most common congenital heart defects diagnosed in children. Sarcomeric genes has been attributed to ASD and knockdown of MYH3 functionally homologues gene in chick models indicated abnormal atrial septal development. Here, we report for the first time, a case-control study investigating the role of MYH3 among non-syndromic ASD patients in contributing to septal...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32315303
DOI: 10.1371/journal.pone.0230982
PMCID: PMC7173802

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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