Article
Genetic variability following selection for scrapie resistance in six autochthonous sheep breeds in the province of Bolzano (northern Italy).
Journal of animal breeding and genetics = Zeitschrift fur Tierzuchtung und Zuchtungsbiologie - 1 Jul 2020
Bordin Fulvio, Dalvit Chiara, Caldon Mauro, Zulian Laura, Colamonico Rosa, Trincanato Simone, Mock Barbara, Reale Stefano, Mutinelli Franco, Granato Anna
Abstract excerpt
Scrapie is an ovine transmissible spongiform encephalopathy, and its susceptibility is associated with polymorphisms in the prion protein gene (PRNP). Genetic selection is currently the most effective mean for eradication of the susceptible VRQ allele in favour of resistant ARR allele. Maintenance of genetic diversity should be one of the major objectives in breeding programmes, especially in endangered breeds,...
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