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Mitochondrial DNA Copy Number in Peripheral Blood Is Reduced in Type 2 Diabetes Patients with Polyneuropathy and Associated with a MIR499A Gene Polymorphism.

DNA and cell biology - 1 Aug 2020

Latini Andrea, Borgiani Paola, De Benedittis Giada, D'Amato Cinzia, Greco Carla, Lauro Davide, Novelli Giuseppe, Spallone Vincenza, Ciccacci Cinzia

Abstract excerpt

Our aim was to evaluate in a cohort of 125 Italian patients with type 2 diabetes (T2D), who underwent neurological evaluation, the possible differences in the number of mitochondrial DNA copies (mtDNA) comparing positive and negative patients for cardiovascular autonomic neuropathy (CAN) or diabetic peripheral neuropathy (DPN) and comparing them with healthy controls. We also investigated a possible correlation...

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Identifiers

PMID: 32311290
DOI: 10.1089/dna.2019.5326

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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