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Testing the Anna Karenina Principle in Human Microbiome-Associated Diseases

25 Mar 2020

Abstract excerpt

The AKP (Anna Karenina principle), which refers to observations inspired by the opening line of Leo Tolstoy's Anna Karenina, "all happy families are all alike; each unhappy family is unhappy in its own way," predicts that all "healthy" microbiomes are alike and each disease-associated microbiome is "sick" in its own way in human microbiome-associated diseases (MADs). The AKP hypothesis predicts the rise of...

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PMID: 32305861
DOI: 10.1016/j.isci.2020.101007

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