Article
Histologic features of melanoma associated with germline mutations of CDKN2A, CDK4, and POT1 in melanoma-prone families from the United States, Italy, and Spain.
Journal of the American Academy of Dermatology - 1 Sept 2020
Sargen Michael R, Calista Donato, Elder David E, Massi Daniela, Chu Emily Y, Potrony Míriam, Pfeiffer Ruth M, Carrera Cristina, Aguilera Paula, Alos Llucia, Puig Susana, Elenitsas Rosalie, Yang Xiaohong R, Tucker Margaret A, Landi Maria Teresa, Goldstein Alisa M
Abstract excerpt
BACKGROUND: CDKN2A, CDK4, and POT1 are well-established melanoma-susceptibility genes. OBJECTIVE: We evaluated melanoma histopathology for individuals with germline mutations of CDKN2A, CDK4, and POT1. METHODS: We assessed histopathology for melanomas diagnosed in melanoma-prone families (≥2 individuals with melanoma) from the United States, Italy, and Spain. Comparisons between mutation carriers and noncarriers...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.