Article
Naturally occurring cell-adapted classic strain of infectious bursal disease virus.
Veterinary microbiology - 1 Apr 2020
Wang Yulong, Fan Linjin, Jiang Nan, Gao Li, Li Kai, Gao Yulong, Liu Changjun, Cui Hongyu, Pan Qing, Zhang Yanping, Wang Xiaomei, Qi Xiaole
Abstract excerpt
Infectious bursal disease virus (IBDV), the etiological agent of infectious bursal disease (IBD), is a variable RNA virus of Avibirnavirus. Some artificially attenuated vaccine strains of IBDV can adapt to cell culture of chicken embryo fibroblast (CEF) cell or its immortalized cell line DF1 in vitro while wild-type IBDV cannot. In this study, for the first time, a naturally occurring cell-adapted classic strain...
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