Article
Copy number variation in human genomes from three major ethno-linguistic groups in Africa.
BMC genomics - 10 Apr 2020
Nyangiri Oscar A, Noyes Harry, Mulindwa Julius, Ilboudo Hamidou, Kabore Justin Windingoudi, Ahouty Bernardin, Koffi Mathurin, Asina Olivier Fataki, Mumba Dieudonne, Ofon Elvis, Simo Gustave, Kimuda Magambo Phillip, Enyaru John, Alibu Vincent Pius, Kamoto Kelita, Chisi John, Simuunza Martin, Camara Mamadou, Sidibe Issa, MacLeod Annette, Bucheton Bruno, Hall Neil, Hertz-Fowler Christiane, Matovu Enock
Abstract excerpt
BACKGROUND: Copy number variation is an important class of genomic variation that has been reported in 75% of the human genome. However, it is underreported in African populations. Copy number variants (CNVs) could have important impacts on disease susceptibility and environmental adaptation. To describe CNVs and their possible impacts in Africans, we sequenced genomes of 232 individuals from three major African...
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