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Article

What's new in IUGR from the endocrinological point of view?

Pediatric endocrinology, diabetes, and metabolism - 1 Jan 2019

Korpysz Alicja, Szalecki Mieczysław

Abstract excerpt

Genetic causes of IUGR: The IGF 2 gene encoding IGF2 synthesis contributes to growth of the foetus. The maternal genes PHLDA2, GRB10, and placental ALS also play a role in the regulation of foetal growth. CDKN1C mutation can lead to IUGR. In SRS syndrome, apart from epimutation 11p15 and disomy 7, the cause may be a mutation of HMAGA2-PLAG1-IGF2 genes. Growth deficiency: in 10% of children with IUGR with growth...

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Identifiers

PMID: 32270973
DOI: 10.5114/pedm.2019.91547

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