Article
Preanalytic variables in quality and quantity of nucleic acids extracted from FNA specimens of thyroid gland nodules collected in CytoLyt: Cellularity and storage time.
Cancer cytopathology - 1 Sept 2020
Heymann Jonas J, Yoxtheimer Lorene M, Park Hyeon Jin, Fernandez Evan M, Facey Kirk E, Alperstein Susan A, Tran Hung V, Baek Inji, Scognamiglio Theresa, Rennert Hanna, Siddiqui Momin T, Song Wei
Abstract excerpt
BACKGROUND: Morphologic and genetic analysis of thyroid nodules may be performed from a single vial. Preanalytic variables that affect nucleic acid extracted from a single vial are evaluated. METHODS: Thyroid fine-needle aspiration (FNA) specimens collected in CytoLyt were evaluated. A ThinPrep slide was prepared. Extracted nucleic acids were analyzed using Oncomine Comprehensive Panel, version 2, after Ion...
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