Article
ARMC5 mutations are associated with high levels of proliferating cell nuclear antigen and the presence of the serotonin receptor 5HT4R in PMAH nodules.
Archives of endocrinology and metabolism - 1 Aug 2020
Conceição Barbara Brito da, Cavalcante Isadora Pontes, Kremer Jean Lucas, Auricino Thais Barabba, Bento Eduarda Corrêa, Zerbini Maria Claudia Nogueira, Fragoso Maria Candida Barisson Villares, Lotfi Claudimara Ferini Pacicco
Abstract excerpt
Objective To analyze the morphological and functional characteristics of primary macronodular adrenal hyperplasia (PMAH) nodules carrying or not carrying ARMC5 mutations and the consequences of the presence of mutations in terms of the pattern of macronodule composition and functional state. Subjects and methods The analyses were performed by hematoxylin-eosin staining, immunohistochemistry, microdissection of...
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