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Nuclear Factor κB (NF-κB)–Mediated Inflammation in Multiple Sclerosis

24 Mar 2020

Abstract excerpt

The nuclear factor κB (NF-κB) signaling cascade has been implicating in a broad range of biological processes, including inflammation, cell proliferation, differentiation, and apoptosis. The past three decades have witnessed a great progress in understanding the impact of aberrant NF-κB regulation on human autoimmune and inflammatory disorders. In this review, we discuss how aberrant NF-κB activation contributes...

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PMID: 32265906
DOI: 10.3389/fimmu.2020.00391

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