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Article

Case contamination in electronic health records based case-control studies.

Biometrics - 1 Mar 2021

Wang Lu, Schnall Jill, Small Aeron, Hubbard Rebecca A, Moore Jason H, Damrauer Scott M, Chen Jinbo

Abstract excerpt

Clinically relevant information from electronic health records (EHRs) permits derivation of a rich collection of phenotypes. Unlike traditionally designed studies where scientific hypotheses are specified a priori before data collection, the true phenotype status of any given individual in EHR-based studies is not directly available. Structured and unstructured data elements need to be queried through...

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PMID: 32246839
DOI: 10.1111/biom.13264

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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