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Development and validation of a survival model for lung adenocarcinoma based on autophagy-associated genes

1 Apr 2020

Abstract excerpt

BACKGROUND: Given that abnormal autophagy is involved in the pathogenesis of cancers, we sought to explore the potential value of autophagy-associated genes in lung adenocarcinoma (LUAD). METHODS: RNA sequencing and clinical data on tumour and normal samples were acquired from The Cancer Genome Atlas (TCGA) database and randomly assigned to training and testing groups. Differentially expressed...

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PMID: 32238163
DOI: 10.1186/s12967-020-02321-z

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