Article
Serine threonine kinase 11/liver kinase B1 mutation in sporadic scirrhous-type gastric cancer cells.
Carcinogenesis - 13 Nov 2020
Nishimura Sadaaki, Yashiro Masakazu, Sera Tomohiro, Yamamoto Yurie, Kushitani Yukako, Sugimoto Atsushi, Kushiyama Shuhei, Togano Shingo, Kuroda Kenji, Okuno Tomohisa, Murakami Yoshiki, Ohira Masaichi
Abstract excerpt
Scirrhous-type gastric carcinoma (SGC), which is characterized by the rapid proliferation of cancer cells accompanied by extensive fibrosis, shows extremely poor survival. A reason for the poor prognosis of SGC is that the driver gene responsible for SGC has not been identified. To identify the characteristic driver gene of SGC, we examined the genomic landscape of six human SGC cell lines of OCUM-1, OCUM-2M,...
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