Article
Efficient Cardiac Differentiation of Human Amniotic Fluid-Derived Stem Cells into Induced Pluripotent Stem Cells and Their Potential Immune Privilege.
International journal of molecular sciences - 29 Mar 2020
Fang Yi-Hsien, Wang Saprina P H, Gao Zi-Han, Wu Sheng-Nan, Chang Hsien-Yuan, Yang Pei-Jung, Liu Ping-Yen, Liu Yen-Wen
Abstract excerpt
Mature mammalian hearts possess very limited regenerative potential. The irreversible cardiomyocyte loss after heart injury can lead to heart failure and death. Pluripotent stem cells (PSCs) can differentiate into cardiomyocytes for cardiac repair, but there are obstacles to their clinical application. Among these obstacles is their potential for post-transplant rejection. Although human amniotic fluid-derived...
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