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Article

HLA-G14bp ins/del polymorphism and post-transplant weight gain in kidney transplantation: potential implications beyond tolerance.

BMC nephrology - 30 Mar 2020

Piancatelli Daniela, Maccarone Daniela, Colanardi Alessia, Sebastiani Pierluigi, Clemente Katia, Iesari Samuele, Lai Quirino, Pisani Francesco

Abstract excerpt

BACKGROUND: Human leukocyte antigen (HLA)-G is a non-classical HLA molecule with immunomodulant and immunosuppressive functions, involved in transplantation tolerance. HLA-G14bp ins/del polymorphism in exon 8 has been associated with allograft rejection and kidney transplant outcome, with controversial results. We investigated associations of HLA-G14bp ins/del polymorphism on onset of some of the main...

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Identifiers

PMID: 32228494
DOI: 10.1186/s12882-020-01752-6
PMCID: PMC7104538

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