Article
Antimicrobial peptide and sequence variation along a latitudinal gradient in two anurans.
BMC genetics - 30 Mar 2020
Cortázar-Chinarro Maria, Meyer-Lucht Yvonne, Van der Valk Tom, Richter-Boix Alex, Laurila Anssi, Höglund Jacob
Abstract excerpt
BACKGROUND: While there is evidence of both purifying and balancing selection in immune defense genes, large-scale genetic diversity in antimicrobial peptides (AMPs), an important part of the innate immune system released from dermal glands in the skin, has remained uninvestigated. Here we describe genetic diversity at three AMP loci (Temporin, Brevinin and Palustrin) in two ranid frogs (Rana arvalis and R....
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