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Article

Viral DNA Binding Protein SUMOylation Promotes PML Nuclear Body Localization Next to Viral Replication Centers.

mBio - 17 Mar 2020

Stubbe Miona, Mai Julia, Paulus Christina, Stubbe Hans Christian, Berscheminski Julia, Karimi Maryam, Hofmann Samuel, Weber Elisabeth, Hadian Kamyar, Hay Ron, Groitl Peter, Nevels Michael, Dobner Thomas, Schreiner Sabrina

Abstract excerpt

Human adenoviruses (HAdVs) have developed mechanisms to manipulate cellular antiviral measures to ensure proper DNA replication, with detailed processes far from being understood. Host cells repress incoming viral genomes through a network of transcriptional regulators that normally control cellular homeostasis. The nuclear domains involved are promyelocytic leukemia protein nuclear bodies (PML-NBs),...

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Identifiers

PMID: 32184235
DOI: 10.1128/mBio.00049-20
PMCID: PMC7078464

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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