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Article

The Role of Polycomb Repressive Complex in Malignant Peripheral Nerve Sheath Tumor.

Genes - 9 Mar 2020

Zhang Xiyuan, Murray Béga, Mo George, Shern Jack F

Abstract excerpt

Malignant peripheral nerve sheath tumors (MPNSTs) are aggressive soft tissue sarcomas that can arise most frequently in patients with neurofibromatosis type 1 (NF1). Despite an increasing understanding of the molecular mechanisms that underlie these tumors, there remains limited therapeutic options for this aggressive disease. One potentially critical finding is that a significant proportion of MPNSTs exhibit...

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Identifiers

PMID: 32182803
DOI: 10.3390/genes11030287
PMCID: PMC7140867

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The Role of Polycomb Repressive Complex in Malignant Peripheral Nerve Sheath Tumor.PMID 32182803Read ↗

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