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Article

Macrophage lineages in heart valve development and disease.

Cardiovascular research - 22 Feb 2021

Kim Andrew J, Xu Na, Yutzey Katherine E

Abstract excerpt

Heterogeneous macrophage lineages are present in the aortic and mitral valves of the heart during development and disease. These populations include resident macrophages of embryonic origins and recruited monocyte-derived macrophages prevalent in disease. Soon after birth, macrophages from haematopoietic lineages are recruited to the heart valves, and bone marrow transplantation studies in mice demonstrate that...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32170926
DOI: 10.1093/cvr/cvaa062
PMCID: PMC8453806

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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