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Article

Mutational diversity in mutY deficient Helicobacter pylori and its effect on adaptation to the gastric environment.

Biochemical and biophysical research communications - 7 May 2020

Kinoshita-Daitoku Ryo, Kiga Kotaro, Sanada Takahito, Ogura Yoshitoshi, Bo Zhu, Iida Tamako, Yokomori Rui, Kuroda Eisuke, Tanaka Mototsugu, Sood Arpana, Suzuki Toshihiko, Nakai Kenta, Hayashi Tetsuya, Mimuro Hitomi

Abstract excerpt

Helicobacter pylori, a pathogenic bacterium that colonizes in the human stomach, harbors DNA repair genes to counter the gastric environment during chronic infection. In addition, H. pylori adapts to the host environment by undergoing antigenic phase variation caused by genomic mutations. The emergence of mutations in nucleotide sequences is one of the major factors underlying drug resistance and genetic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32164943
DOI: 10.1016/j.bbrc.2020.02.087

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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