Article
Recurrent Germline BRCA2 Gene Mutation in Lithuanian Family.
Medicina (Kaunas, Lithuania) - 10 Mar 2020
Sadzevičienė Ieva, Jarmalaitė Sonata, Besusparis Justinas, Liaugaudienė Olga, Asadauskienė Jolita, Brasiūnienė Birutė, Kulikienė Ilona, Sabaliauskaitė Rasa
Abstract excerpt
Approximately 10% of all breast cancer (BC) cases are familial and caused by inheritance of mutant BRCA1, BRCA2, or some other genes from the same DNA reparation pathway. Genetic counseling in families with cancer history is a powerful means for early cancer detection and active risk reduction through preventive interventions. This is the first report of the rare inherited BRCA2 frameshift-deletion mutation...
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