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Article

Multi-Dimensional Flow Cytometry Analyses Reveal a Dichotomous Role for Nitric Oxide in Melanoma Patients Receiving Immunotherapy.

Frontiers in immunology - 1 Jan 2020

Garg Saurabh K, Ott Matthew J, Mostofa A G M, Chen Zhihua, Chen Y Ann, Kroeger Jodi, Cao Biwei, Mailloux Adam W, Agrawal Alisha, Schaible Braydon J, Sarnaik Amod, Weber Jeffrey S, Berglund Anders E, Mulé James J, Markowitz Joseph

Abstract excerpt

Phenotyping of immune cell subsets in clinical trials is limited to well-defined phenotypes, due to technological limitations of reporting flow cytometry multi-dimensional phenotyping data. We developed a multi-dimensional phenotyping analysis tool and applied it to detect nitric oxide (NO) levels in peripheral blood immune cells before and after adjuvant ipilimumab co-administration with a peptide vaccine in...

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Identifiers

PMID: 32161584
DOI: 10.3389/fimmu.2020.00164
PMCID: PMC7052497

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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