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Article

Hypophosphatemic rickets: A rare complication of congenital melanocytic nevus syndrome.

Pediatric dermatology - 1 May 2020

Welfringer-Morin Anne, Pinto Graziella, Baujat Geneviève, Vial Yoann, Hadj-Rabia Smail, Bodemer Christine, Boccara Olivia

Abstract excerpt

We report the case of a child who presented with a giant melanocytic nevus with numerous satellite nevi at birth and developed hypophosphatemic rickets due to excessive secretion of the FGF23 hormone. A NRAS c.182A>G (Q61R) mutation was identified in the lesional skin. The functional outcome was favorable with medical treatment.

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 32157705
DOI: 10.1111/pde.14139

Genes

FGF23
NRAS

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

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Research trail→

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Hypophosphatemic rickets: A rare complication of congenital melanocytic nevus syndrome.PMID 32157705Read ↗

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Multilineage somatic activating mutations in HRAS and NRAS cause mosaic cutaneous and skeletal lesions, elevated FGF23 and hypophosphatemia.Semantic proximity Read ↗

An update on congenital melanocytic nevus syndrome: A case report and literature review.Semantic proximity Read ↗

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