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Targeted next generation sequencing of nine osteoporosis-related genes in the Wnt signaling pathway among Chinese postmenopausal women.

Endocrine - 1 Jun 2020

Li Can, Huang Qin, Yang Rui, Guo Xiaodong, Dai Yu, Zeng Junchao, Zeng Yun, Tao Lailin, Li Xiaolong, Zhou Haolong, Wang Qi

Abstract excerpt

PURPOSE: This study aimed to explore the association between low-frequency and rare variants of Wnt signaling genes and postmenopausal osteoporosis (OP) by the next generation sequencing (NGS) technology. METHODS: We performed targeted NGS of nine Wnt signaling genes in 400 Chinese postmenopausal women, including 226 cases with decreased bone mineral density (BMD) and 174 controls with normal values. Proxy...

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PMID: 32147773
DOI: 10.1007/s12020-020-02248-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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