Article
Role of FGF and Hyaluronan in Choroidal Neovascularization in Sorsby Fundus Dystrophy.
Cells - 4 Mar 2020
Wolk Alyson, Hatipoglu Dilara, Cutler Alecia, Ali Mariya, Bell Lestella, Hua Qi Jian, Singh Rupesh, Batoki Julia, Karle Laura, Bonilha Vera L, Wessely Oliver, Stoehr Heidi, Hascall Vincent, Anand-Apte Bela
Abstract excerpt
Sorsby's fundus dystrophy (SFD) is an inherited blinding disorder caused by mutations in the tissue inhibitor of metalloproteinase-3 (TIMP3) gene. The SFD pathology of macular degeneration with subretinal deposits and choroidal neovascularization (CNV) closely resembles that of the more common age-related macular degeneration (AMD). The objective of this study was to gain further insight into the molecular...
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