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Article

Young and Restless: Expansion of Donor-Origin Mutant HSCs after Transplantation.

Cell stem cell - 5 Mar 2020

Steensma David P

Abstract excerpt

In a study of young adults chosen as unrelated hematopoietic stem cell donors for patients with hematological malignancies, leukemia-associated mutations were detectable in cells from 44% of donors. Donor-origin mutant clones engrafted in recipients and expanded during the first 100 days after transplant, but donor-derived leukemia was not observed.

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Identifiers

PMID: 32142660
DOI: 10.1016/j.stem.2020.01.022

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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