Article
Plasma Ceramides and Sphingomyelins of Pediatric Patients Increase in Primary Ciliary Dyskinesia but Decrease in Cystic Fibrosis.
Lipids - 1 May 2020
Bal Topçu Dilara, Tugcu Gokcen, Ozcan Filiz, Aslan Mutay, Yalcinkaya Ahmet, Polat Sanem Eryilmaz, Hizal Mina, Yalcin Ebru Elmas, Ersoz Deniz Dogru, Ozcelik Ugur, Kiper Nural, Lay Incilay, Oztas Yesim
Abstract excerpt
We investigated plasma sphingomyelin (CerPCho) and ceramide (Cer) levels in pediatric patients with cystic fibrosis (CF) and primary ciliary dyskinesia (PCD). Plasma samples were obtained from CF (n = 19) and PCD (n = 7) patients at exacerbation, discharge, and stable periods. Healthy children (n = 17) of similar age served as control. Levels of 16-24 CerPCho and 16-24 Cer were measured by LC-MS/MS....
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