Article
Alveolar macrophage phenotypes in severe equine asthma.
Veterinary journal (London, England : 1997) - 1 Feb 2020
Wilson M E, McCandless E E, Olszewski M A, Robinson N Edward
Abstract excerpt
Because the alveolar macrophage (AM) phenotype of horses with severe equine asthma (SEA) is unknown, the cytokines expressed by M1- and M2-polarized AM were determined and the hypothesis that natural hay/straw challenge (NC) induces divergent AM phenotypes in control horses and horses with SEA was tested. Macrophages from control horses were activated either with eIFNγ + lipolysaccharide (LPS) or eIL-4 to...
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