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Article

CircMUC16 promotes autophagy of epithelial ovarian cancer via interaction with ATG13 and miR-199a

28 Feb 2020

Abstract excerpt

BACKGROUND: Circular RNA (circRNA) has been proven to play a significant role in multiple types of cancer. However, the expression and role of circRNAs in epithelial ovarian cancer (EOC) remains elusive. METHODS: CircRNA and mRNA expression profiles of EOC were screened with sequencing analysis. Gene silencing and over-expression were used to study circRNA function. Cell proliferation and Matrigel invasion assays...

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PMID: 32111227
DOI: 10.1186/s12943-020-01163-z

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