SLC5A2 mutations, including two novel mutations, responsible for renal glucosuria in Chinese families.

Abstract excerpt

BACKGROUND: Familial renal glucosuria (FRG) is characterized by persistent glucosuria without other impairments of tubular function in the presence of normal serum glucose. SGLT2, which is almost exclusively expressed in the kidney, accounts for most of the glucose reabsorption. Recently, some studies have confirmed that SLC5A2 mutations are responsible for the pathogenesis of familial renal glucosuria, but FRG...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Amino Acids
• Share to Asian People
• Share to Cell Line