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Article

Genetic analysis and literature review of Chinese patients with familial renal glucosuria: Identification of a novel SLC5A2 mutation.

Clinica chimica acta; international journal of clinical chemistry - 1 Jun 2017

Wang Xiaojing, Yu Miao, Wang Tong, Zhang Huabing, Ping Fan, Zhang Qian, Xu Jianping, Feng Kai, Xiao Xinhua

Abstract excerpt

BACKGROUND: Familial renal glucosuria (FRG) is an inherited renal tubular disorder characterized by persistent isolated glucosuria with normal blood glucose. SLC5A2 gene mutation was the causative of FRG. METHODS: Molecular genetic analysis of SLC5A2 gene by Sanger sequencing was conducted in two unrelated non-consanguineous Chinese families with isolated glucosuria. Extensive laboratory test and physical...

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PMID: 28365451
DOI: 10.1016/j.cca.2017.03.027

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