Article
Lack of Association of Generic Brittle Status with Genetics and Physiologic Measures in Patients with Epilepsy.
Pharmaceutical research - 26 Feb 2020
Das Sharmila, Guo Dong, Jiang Xiaohui, Jiang Wenlei, Shu Yan, Ting Tricia Y, Polli James E
Abstract excerpt
PURPOSE: A patient was denoted to be generic brittle (GB) if they had a negative opinion about generics (e.g. prior history of a switch problem) or took the innovator brand of their most problematic anti-epileptic drug (AED) when generic was available. The aim of this hypothesis-generating study was to assess possible genetic and physiologic differences between GB and not GB patients with epilepsy. METHODS:...
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