Article
Genetic Diversity and Characteristics of Drug Resistance Among Treatment-Naive People Living with HIV in Xi'an, China.
Drug design, development and therapy - 1 Jan 2023
Xia Huan, Jin Juan, Ba Huanhuan, Zhang Yuan, Li Jiajia, Guo Rui, Li Ying, Ma Ping, Zhang Yan
Abstract excerpt
Purpose: The genetic diversity and genetic predisposition for drug resistance mutations are the primary features of human immunodeficiency virus type 1 (HIV-1), which could cause the incidence of failure of antiretroviral therapy (ART). This study investigates the distribution of various HIV-1 genotypes and the incidence of pretreatment drug resistance (PDR) in the antiretroviral-naive HIV-1 infected participants...
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