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T2-FLAIR Mismatch Sign Is Caused by Long T1 and T2 of IDH-mutant, 1p19q Non-codeleted Astrocytoma.

Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine - 1 Mar 2021

Kinoshita Manabu, Uchikoshi Masato, Sakai Mio, Kanemura Yonehiro, Kishima Haruhiko, Nakanishi Katsuyuki

Abstract excerpt

T2-fluid-attenuated inversion recovery images (FLAIR) mismatch sign is now known to be a specific yet insensitive image feature for IDH-mutant, 1p19q non-codeleted astrocytoma. The current study revealed that lesion presenting T2-FLAIR mismatch exhibited extremely long T1- and T2-relaxation time while T2-FLAIR matched lesions showed low to moderate values. On the other hand, IDH-wildtype tumors presented...

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PMID: 32101817
DOI: 10.2463/mrms.bc.2019-0196
PMCID: PMC7952199

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