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Article

The role of Apolipoprotein E epsilon4 in the association between psychosocial working conditions and dementia.

Aging - 20 Feb 2020

Pan Kuan-Yu, Xu Weili, Mangialasche Francesca, Grande Giulia, Fratiglioni Laura, Wang Hui-Xin

Abstract excerpt

In this population-based prospective study, we examined the association of job demand-control combinations with dementia, and explored the roles of Apolipoprotein E epsilon4 (APOE ɛ4) and work duration in this association. A total of 2,579 dementia-free individuals aged 60+ years from Sweden were followed over 12 years. Dementia diagnosis was made by physicians. Lifelong occupational experience was collected, and...

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PMID: 32081835
DOI: 10.18632/aging.102843
PMCID: PMC7066897

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