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Article

Systems biology-based approaches to summarize and identify novel genes and pathways associated with acute and chronic postsurgical pain.

Journal of clinical anesthesia - 1 Jun 2020

Chidambaran Vidya, Ashton Maria, Martin Lisa J, Jegga Anil G

Abstract excerpt

STUDY OBJECTIVE: To employ systems biology-based machine learning to identify biologic processes over-represented with genetic variants (gene enrichment) implicated in post-surgical pain. DESIGN: Informed systems biology based integrative computational analyses. SETTING: Pediatric research and teaching institution. INTERVENTIONS: Pubmed search (01/01/2001-10/31/2017) was performed to identify "training" genes...

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Identifiers

PMID: 32058259
DOI: 10.1016/j.jclinane.2020.109738
PMCID: PMC7276001

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