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Article

Genome-wide analysis of the role of DNA methylation in inbreeding depression of reproduction in Langshan chicken.

Genomics - 1 Jul 2020

Han Wei, Xue Qian, Li Guohui, Yin Jianmei, Zhang Huiyong, Zhu Yunfen, Xing Weijie, Cao Yuxia, Su Yijun, Wang Kehua, Zou Jianmin

Abstract excerpt

Inbreeding depression of chicken reproduction is a major concern in the conservation of chicken genetic resources. To investigate the potential DNA methylation sites involved in the inbreeding depression of chicken reproduction, we carried out whole-genome bisulfite sequencing (WGBS) of hypothalamus and ovary tissues from the strongly and weakly inbred Langshan chickens, respectively. 5948 and 4593 differentially...

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PMID: 32057912
DOI: 10.1016/j.ygeno.2020.02.007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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