Article
Two common mitochondrial DNA polymorphisms are highly associated with migraine headache and cyclic vomiting syndrome.
Cephalalgia : an international journal of headache - 1 Jul 2009
Zaki E A, Freilinger T, Klopstock T, Baldwin E E, Heisner K R U, Adams K, Dichgans M, Wagler S, Boles R G
Abstract excerpt
Mitochondrial dysfunction is a hypothesized component in the multifactorial pathogenesis of migraine without aura (MoA, 'common migraine') and the related condition of cyclic vomiting syndrome (CVS). In this study, the entire mitochondrial genome was sequenced in 20 haplogroup-H CVS patients, a subject group studied because of greater genotypic and phenotypic homogeneity. Sequences were compared against...
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