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Article

Association analysis of loci implied in "buffering" epistasis.

Journal of animal science - 1 Mar 2020

Reverter Antonio, Vitezica Zulma G, Naval-Sánchez Marina, Henshall John, Raidan Fernanda S S, Li Yutao, Meyer Karin, Hudson Nicholas J, Porto-Neto Laercio R, Legarra Andrés

Abstract excerpt

The existence of buffering mechanisms is an emerging property of biological networks, and this results in the buildup of robustness through evolution. So far, there are no explicit methods to find loci implied in buffering mechanisms. However, buffering can be seen as interaction with genetic background. Here we develop this idea into a tractable model for quantitative genetics, in which the buffering effect of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 32047922
DOI: 10.1093/jas/skaa045
PMCID: PMC7067535

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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