Article
A novel gene-wide haplotype at the macrophage migration inhibitory factor (MIF) locus is associated with endometrioma.
European journal of obstetrics, gynecology, and reproductive biology - 1 Apr 2020
Chekini Zahra, Poursadoughian Yaran Atiyeh, Ansari-Pour Naser, Shahhoseini Maryam, Ramazanali Fariba, Aflatoonian Reza, Afsharian Parvaneh
Abstract excerpt
OBJECTIVE: Endometriosis is a common complex gynecological disorder that may result in infertility. Macrophage migration inhibitory factor (MIF) is a key pro-inflammatory cytokine that is overexpressed in endometriosis tissues. However, hitherto, no study tested the possible relevancy at genetic level. The aim of this study was to evaluate MIF polymorphisms and possible associations between haplotype of the gene...
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