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Article

Genetic association study of SOX2 gene polymorphisms with high myopia in a Chinese population.

European journal of ophthalmology - 1 Mar 2021

Li Lan, Cui Ying Juan, Zou Yunchun, Yang Liyuan, Yin Ximin, Li Bo, Yan Liying

Abstract excerpt

PURPOSE: The aim of this study is to investigate whether SOX2 gene variants were associated with high myopia in a Chinese population. METHODS: This study is conducted using case-control association analysis. This study recruited 83 healthy controls (with binocular spherical equivalent between -0.50 and +0.50 D) and 117 high myopia cases (spherical equivalent > -6.00 D in both eyes). Three single-nucleotide...

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PMID: 32037877
DOI: 10.1177/1120672120904666

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