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Article

Crosstalk between autophagy and metabolic regulation of cancer stem cells

6 Feb 2020

Abstract excerpt

Cancer is now considered as a heterogeneous ecosystem in which tumor cells collaborate with each other and with host cells in their microenvironment. As circumstances change, the ecosystem evolves to ensure the survival and growth of the cancer cells. In this ecosystem, metabolism is not only a key player but also drives stemness. In this review, we first summarize our current understanding of how autophagy...

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PMID: 32028963
DOI: 10.1186/s12943-019-1126-8

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